As many old city´s Seville is not a good place to driving & parking. Because of the one way and narrow streets and is very hard parking on the streets, we only recommend renting a car in case you want to visit city’s and towns around Seville.
If you park on the street look for loading and disable signs and blue lines indicate that you have to pay for parking there. Car crime is low just don´t leave anything inside the car and put the mirrors in.
You got a few public parking around the city center, some of them got special rate for 4 days, weeks, or months, ask at the office when you get in.